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Sleep bulletin n. 2 | April 2021
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"Sleep and wakefulness, both of them, when immoderate constitute disease"
(Hippocrates)
Sleep and Breathing conference
16th-17th April, 2021
On 16th-17th April 2021 the conference Sleep and Breathing 2021 took place virtually. The Sleep and Breathing conference is the largest pan-European meeting of its kind and offers an integrated approach to the investigation and treatment of sleep and respiratory disorders. This year the conference focused on professional development and education, in particular, in the field of sleep respiratory medicine and science. (programme online).
We would like to draw your attention to the multidisciplinary nature of sleep-disordered breathing which is summarized in a brief overview by Dr. Oana Deleanu.
The clinical case presented by Dr. Simon D. Herkenrath demonstrates the complexity of diagnostics and treatment of sleep apnea comorbid with neurological pathology (Chiari malformation)
Science
Sleep-disordered breathing as a multidisciplinary disease: The pulmonologist’s point of view - Oana Claudia Deleanu, MD, PhD, Lecturer at University of Medicine and Pharmacy, Bucharest, Romania
Sleep-related breathing disorders (SRBDs) are characterized by abnormal respiration during sleep and include a wide spectrum of disorders, e.g. obstructive sleep apnea (OSA), central sleep apnea (CSA), sleep-related hypoventilation, sleep-related hypoxemia disorder etc. The knowledge of normal sleep physiology is essential for understanding SRBDs pathophysiology. Normal sleep is composed of two major phases, NREM (non-rapid eye-movement) sleep and REM (rapid eye movements) sleep. NREM is the predominant one and is characterized by cardiovascular balance due to higher parasympathetic tone which controls the homeostasis and leads to the reduction in heart rate and blood pressure.
REM sleep is characterized by eye movement, muscle twitches and skeletal muscle atonia. It is constituted of tonic and phasic stages. Unlike NREM phase, REM is dominated by cardiovascular instability. Heart rate and blood pressure vary a lot during REM sleep depending on switching parasympathetic or symphatetic control...
Education
Sleep is...
“If sleep does not serve an absolutely vital function, then it will be the biggest mistake the evolutionary process has ever made” (Allan Rechtschaffen)
On World Health Day, it is important to bring attention to sleep and its role in our life. Regular and sound sleep is essential for maintaining mental and physical health and for disease prevention. Sleep plays various functions in our life, including information processing, memory consolidation, metabolism regulation, toxin clearance, immune regulation and many other vital functions. And many more are still to be discovered in future.
We offer you a video about functions of sleep produced for the Brain Awareness week with the support of Dana Foundation.
Sleep sound, stay healthy!
CSA in Chiari Malformation
CLINICAL CASE
Dr. med. Simon D. Herkenrath – Institute of Pneumology, University of Cologne, Germany
Chiari malformation type I, a disease characterized by the herniation of the cerebellar tonsils through the Foramen magnum into the upper spinal canal, may indirectly lead to impairment of pharyngeal as well as laryngeal muscles promoting upper airway collapse. Altered CO2 chemosensitivity is additionally described adding to a destabilized breathing pattern. In our case, a 44 year old, extremely obese woman with Chiari malformation type I and a history of obstructive sleep apnea presented to our sleep lab for re-evaluation after unsuccessful CPAP and bi-level therapy.
Events
World Sleep Forum
5th Think Tank on neurodegenaration related to sleep
Virtual Meeting | 27th - 29th May 2021
The general topic of the meeting concern different aspects of neurodegeneration and sleep disorders, from the basic mechanism on neurodegeneration and related to sleep to the risk of mild cognitive impairment and Alzheimer disease, from sleep apnea to cognition and pharmacological risk of dementia.
For the first time, this year, the World Sleep Forum will include 2 “Public Key-note Lectures” session open to all interested participants.
2nd Sleep Medicine Summer School
Grenoble | 5th - 9th July 2021
This year the Sleep Medicine Summer School will offer an intense scientific program on the topics of chronobiology and circadian disorders, hypersomnia and in particular hypersomnolence in neurological disorders, insomnia and mental health, sleep and psychiatry, sleep and neurologic disorders with a specific focus on epilepsy, movement disorders, parasomnias and disorders of arousals, and sleep related breathing disorders with a specific focus on personalized medicine.
PLEASE NOTE: in consideration of the current pandemic situation, participants can pre-register for free.
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